Endoscopic & Pathologic findings (Sci Rep (Nature research), 2022)
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Representative endoscopic fndings associated with autoimmune gastritis. Endoscopic fndings of O4 with vascular visibility in the entire area of the greater curvature of the corpus (a). O3 with spared vascular visibility in a part of the greater curvature of the corpus (b). O2 with spared vascular visibility in the entire area of the greater curvature of the corpus (c). O1 with vascular visibility in the lesser curvature of the corpus (d). Te endoscopic atrophic border is indicated by a dotted line (b–d). Endoscopic fndings of corpus-predominant advanced atrophy (O4) with a non-atrophic antral part (antrum [e1] and corpus [e2]). Endoscopic fndigs of the disappearance of the fold in the greater curvature of the gastric body (a, b, e2). Typical endoscopic fndings of sticky adherent dense mucous (f) and multiple hyperplastic polyps in the proximal stomach (g).
Targeted histological fndings of autoimmune gastritis. Oxyntic mucosal atrophy with lymphocytic infltrates (a). Epithelium of pseudo-pyloric (b) and intestinal metaplasia (c). Difuse lymphocyte cell infltration, which is heavier in the deep portion than in the lamina propria (d). Increased proportion of gastric pits (bold line) induced by severe atrophy, which was defned as the proportion of gastric pits (bold line)/gastric duct (thin line) (e). Enterochromafn-like cell hyperplasia (arrowhead) (f).
<참고자료>
Relevance of pepsinogen, gastrin, and endoscopic atrophy in the diagnosis of autoimmune gastritis
Scientific Reports (Nature research) 2022 Mar 10;12(1):4202.